Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979898 | 0.93 | HPGD (0.48) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19980126 | 0.91 | HPGD (0.43) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL19979955 | 0.89 | HPGD (0.39) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19980213 | 0.87 | POLB (0.44) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL19980217 | 0.79 | GAA (0.38) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL19980104 | 0.76 | KDM4E (0.39) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL19980105 | 0.73 | MAPT (0.44) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19979894 | 0.73 | KDM4E (0.40) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 | |
| SCHEMBL19979834 | 0.73 | POLB (0.47) | RAB9ACYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL19980177 | 0.73 | POLB (0.41) | CYP1A2CYP2C9CYP2C19HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |