Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FOS | P01100 | 2/20 | 0.36 |
| ▸ | JUN | P05412 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980105 | 0.79 | MAPT (0.44) | KDM4EMAPTALDH1A1TGFBR1GAA | |
| SCHEMBL19980130 | 0.74 | POLB (0.41) | GAAPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL19979876 | 0.74 | TUBB4A (0.35) | GAATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1498542 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL31697314 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL23169063 | 0.72 | MEN1 (0.49) | KDM4EMAPTALDH1A1HPGDTP53 | |
| SCHEMBL28944494 | 0.72 | KDM4E (0.48) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL29827383 | 0.72 | KDM4E (0.48) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL24834467 | 0.72 | KDM4E (0.48) | KDM4EMAPTALDH1A1HSD17B10CA12 | |
| SCHEMBL4192553 | 0.72 | KDM4E (0.58) | KDM4EMAPTALDH1A1TGFBR1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |