Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156890 | 0.83 | KMT2A (0.38) | POLB | |
| SCHEMBL22048136 | 0.81 | MEN1 (0.37) | POLBMAPK1 | |
| SCHEMBL19980300 | 0.79 | SLC6A2 (0.40) | MAPK1 | |
| SCHEMBL20344529 | 0.74 | KMT2A (0.41) | POLBMAPK1 | |
| SCHEMBL19980155 | 0.74 | STAT3 (0.32) | POLB | |
| SCHEMBL19980141 | 0.74 | STAT3 (0.32) | POLB | |
| SCHEMBL1241206 | 0.72 | TAAR1 (0.50) | CCR5PYCR1 | |
| SCHEMBL23189014 | 0.69 | — | — | |
| SCHEMBL21156308 | 0.68 | SLC6A2 (0.39) | PYCR1 | |
| SCHEMBL27337210 | 0.68 | CCR5 (0.44) | CCR5POLBMAPK1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2956452-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2018-03-21 | — | — | EP | disclosed |