Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956120 | 0.87 | ALDH1A1 (0.49) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL17288793 | 0.86 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL23189106 | 0.84 | MEN1 (0.38) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL17288792 | 0.84 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL12467195 | 0.78 | KMT2A (0.42) | KMT2AALDH1A1 | |
| SCHEMBL15956383 | 0.77 | MAPT (0.45) | ALDH1A1MAPTNPC1 | |
| SCHEMBL24939143 | 0.75 | SMN1; SMN2 (0.38) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL1515627 | 0.71 | ALDH1A1 (0.49) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL17321298 | 0.70 | MEN1 (0.36) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL28164053 | 0.70 | EPHX2 (0.33) | KMT2AALDH1A1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342771-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-11-25 | — | — | EP | disclosed |
| EP-3375780-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-06-03 | — | — | EP | disclosed |
| EP-3508484-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-07-10 | — | — | EP | disclosed |
| EP-3342771-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2018-07-04 | — | — | EP | disclosed |
| EP-2956452-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2018-03-21 | — | — | EP | disclosed |