Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956120 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL17288793 | 0.86 | ALDH1A1 (0.47) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL19980443 | 0.84 | KMT2A (0.38) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL17288792 | 0.84 | ALDH1A1 (0.36) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL15956383 | 0.80 | MAPT (0.45) | NPC1ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL17321298 | 0.73 | MEN1 (0.36) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL14213302 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL19228450 | 0.71 | ALDH1A1 (0.49) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL24130013 | 0.71 | ALDH1A1 (0.39) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28164053 | 0.70 | EPHX2 (0.33) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2021-04-07 | — | — | EP | disclosed |