Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13206328 | 0.93 | ESRRG (0.42) | MAPTRAB9ANPC1THRBMEN1 | |
| SCHEMBL14679866 | 0.92 | THRB (0.43) | MAPTRAB9ANPC1THRBTDP1 | |
| SCHEMBL15003869 | 0.88 | THRB (0.38) | MAPTRAB9ANPC1THRBMEN1 | |
| SCHEMBL19981010 | 0.84 | THRB (0.38) | THRBTDP1L3MBTL1PHLPP2TSHR | |
| SCHEMBL19904030 | 0.84 | TSHR (0.49) | MAPTTHRBTDP1L3MBTL1PHLPP2 | |
| SCHEMBL622489 | 0.83 | MMP14 (0.47) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL10119273 | 0.83 | MMP14 (0.47) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL23028900 | 0.81 | MAPT (0.41) | MAPTRAB9ANPC1THRBMEN1 | |
| SCHEMBL23028973 | 0.81 | MAPT (0.40) | MAPTRAB9ANPC1THRBMEN1 | |
| SCHEMBL10039848 | 0.81 | THRB (0.44) | MAPTRAB9ANPC1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |