Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14679866 | 0.92 | THRB (0.43) | THRBPHLPP2TSHRALDH1A1CYP3A4 | |
| SCHEMBL19980951 | 0.84 | MAPT (0.38) | THRBPHLPP2TSHRALDH1A1CYP3A4 | |
| SCHEMBL19904030 | 0.84 | TSHR (0.49) | THRBPHLPP2TSHRALDH1A1CYP3A4 | |
| SCHEMBL18633382 | 0.82 | PHLPP2 (0.38) | THRBPHLPP2TSHRALDH1A1CYP3A4 | |
| SCHEMBL10608569 | 0.79 | THRB (0.44) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL21322323 | 0.78 | PHLPP2 (0.47) | THRBPHLPP2TSHRALDH1A1CYP3A4 | |
| SCHEMBL13206328 | 0.78 | ESRRG (0.42) | THRBPHLPP2TSHRALDH1A1CYP3A4 | |
| SCHEMBL19980872 | 0.77 | ALDH1A1 (0.42) | PHLPP2TSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL14341772 | 0.77 | THRB (0.43) | THRBTSHRALDH1A1CYP3A4TP53 | |
| SCHEMBL9174872 | 0.77 | THRB (0.57) | THRBTSHRALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008096-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-06-26 | — | — | EP | disclosed |
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |