Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL1420077 | 0.94 | ACHE (0.53) | ACHETSHRLMNAALOX12MAOA | |
| M-Xylene SCHEMBL1420161 | 0.92 | ACHE (0.63) | ACHETSHRLMNAALOX12MAOA | |
| SCHEMBL19503240 | 0.92 | TSHR (0.55) | ACHETSHRLMNAALOX12MAOA | |
| SCHEMBL20829312 | 0.92 | DHODH (0.53) | ACHETSHRLMNAALOX12MAOA | |
| SCHEMBL28043537 | 0.90 | TSHR (0.53) | ACHETSHRLMNAALOX12MAOA | |
| SCHEMBL28376833 | 0.89 | MAOA (0.56) | ACHETSHRLMNAALOX12MAOA | |
| SCHEMBL200730 | 0.89 | ACHE (0.58) | ACHETSHRLMNAALOX12MAOA | |
| Benzene SCHEMBL27980187 | 0.89 | ACHE (0.58) | ACHETSHRLMNAALOX12MAOA | |
| SCHEMBL29699277 | 0.89 | ACHE (0.58) | ACHETSHRLMNAALOX12MAOA | |
| Biphenyl SCHEMBL28828599 | 0.88 | ACHE (0.79) | ACHETSHRLMNAALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9010318-B2 | Extended-range heat transfer fluid using variable composition | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-04-21 | — | — | US | disclosed |
| US-20110146959-A1 | EXTENDED-RANGE HEAT TRANSFER FLUID USING VARIABLE COMPOSITION | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-06-23 | — | — | US | disclosed |