Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21117538 | 0.84 | BTK (0.37) | PTGER4HDAC1HDAC2ALDH1A1MAPT | |
| SCHEMBL19981012 | 0.84 | HDAC1 (0.33) | PTGER4HDAC1HDAC2ALDH1A1MAPT | |
| SCHEMBL22212876 | 0.81 | HDAC1 (0.46) | PTGER4HDAC1HDAC2TSHR | |
| SCHEMBL24006780 | 0.79 | S100B (0.41) | S100BALDH1A1MAPTKDM4EGAA | |
| SCHEMBL17550792 | 0.79 | S100B (0.61) | S100BALDH1A1MAPTGAATSHR | |
| SCHEMBL27095757 | 0.76 | S100B (0.49) | S100BALDH1A1MAPTKDM4EGAA | |
| SCHEMBL24006368 | 0.76 | ALDH1A1 (0.38) | S100BHDAC1ALDH1A1MAPTKDM4E | |
| SCHEMBL18562084 | 0.73 | KMT2A (0.37) | ALDH1A1MAPTHPGDTSHRLMNA | |
| SCHEMBL6573501 | 0.73 | S100B (0.35) | S100B | |
| SCHEMBL6571429 | 0.73 | ALDH1A1 (0.36) | S100BALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |