Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980985 | 0.90 | HDAC1 (0.38) | HDAC1PTGER4HDAC2BTKTSHR | |
| SCHEMBL19980998 | 0.88 | POLB (0.30) | POLBAPEX1HTTTDP1 | |
| SCHEMBL19980987 | 0.86 | MTNR1B (0.35) | HDAC1PTGER4POLBHDAC2ALDH1A1 | |
| SCHEMBL19980976 | 0.85 | HDAC1 (0.41) | HDAC1POLBAPEX1HTTTDP1 | |
| SCHEMBL21117538 | 0.84 | BTK (0.37) | HDAC1PTGER4HDAC2BTKTHRB | |
| SCHEMBL19980980 | 0.84 | S100B (0.37) | HDAC1PTGER4HDAC2BTKTSHR | |
| SCHEMBL19980954 | 0.81 | PHLPP2 (0.40) | POLBAPEX1HTTTDP1BTK | |
| SCHEMBL19980979 | 0.80 | S100B (0.48) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL22212876 | 0.78 | HDAC1 (0.46) | HDAC1PTGER4HDAC2TSHR | |
| SCHEMBL19980921 | 0.75 | PHLPP2 (0.44) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |