SCHEMBL19981147 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	BMP1	P13497	7/20	0.51

▸	ATM	Q13315	1/20	0.39

▸	ADAMTS5	Q9UNA0	1/20	0.38

▸	TDP1	Q9NUW8	1/20	0.38

▸	EPHX2	P34913	1/20	0.37

▸	KCNH2	Q12809	1/20	0.37

▸	CTPS1	P17812	4/20	0.37

▸	KDM4E	B2RXH2	2/20	0.37

▸	PDF	Q9HBH1	1/20	0.36

▸	GLA	P06280	1/20	0.35

▸	DPP4	P27487	1/20	0.34

▸	DPP8	Q6V1X1	1/20	0.34

▸	DPP9	Q86TI2	1/20	0.34

▸	DPP7	Q9UHL4	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19981138	0.91	BMP1 (0.49)	BMP1ATMADAMTS5TDP1EPHX2
SCHEMBL19981145	0.86	BMP1 (0.49)	BMP1ATMADAMTS5TDP1EPHX2
SCHEMBL19981128	0.84	BMP1 (0.44)	BMP1ATMADAMTS5TDP1EPHX2
SCHEMBL19981271	0.82	BMP1 (0.43)	BMP1ATMADAMTS5TDP1EPHX2
SCHEMBL19981337	0.80	BMP1 (0.42)	BMP1ATMADAMTS5TDP1EPHX2
SCHEMBL19866982	0.74	VSIR (0.45)	BMP1ATMADAMTS5TDP1EPHX2
SCHEMBL18077937	0.74	VSIR (0.45)	BMP1ATMADAMTS5TDP1EPHX2
SCHEMBL19981126	0.73	BMP1 (0.33)	BMP1KDM4EDPP4DPP8DPP9
SCHEMBL19981344	0.73	BMP1 (0.41)	BMP1ATMADAMTS5TDP1EPHX2
SCHEMBL19981238	0.70	BMP1 (0.42)	BMP1CTPS1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018051254-A1	CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS	AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN)	2018-03-22	—	—	WO	disclosed