Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | Q9HBH1 | 1/20 | 0.32 | |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981134 | 0.91 | BMP1 (0.39) | BMP1KDM4EGLATDP1VSIR | |
| SCHEMBL19981329 | 0.87 | VSIR (0.44) | BMP1KDM4EGLATDP1VSIR | |
| SCHEMBL19981271 | 0.85 | BMP1 (0.43) | BMP1KDM4EGLATDP1L3MBTL1 | |
| SCHEMBL19866982 | 0.85 | VSIR (0.45) | BMP1TDP1VSIRCD274L3MBTL1 | |
| SCHEMBL18077937 | 0.85 | VSIR (0.45) | BMP1TDP1VSIRCD274L3MBTL1 | |
| SCHEMBL19981128 | 0.84 | BMP1 (0.44) | BMP1KDM4EGLATDP1L3MBTL1 | |
| SCHEMBL19981324 | 0.83 | BMP1 (0.36) | BMP1KDM4EGLATDP1MMP12 | |
| SCHEMBL19981344 | 0.81 | BMP1 (0.41) | BMP1KDM4EGLATDP1L3MBTL1 | |
| SCHEMBL19981147 | 0.80 | BMP1 (0.51) | BMP1KDM4EGLATDP1PDF | |
| SCHEMBL19981139 | 0.80 | POLB (0.40) | BMP1KDM4ETDP1MMP12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |