Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | BMP1 | P13497 | 5/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981126 | 0.90 | BMP1 (0.33) | KDM4ELMNAALDH1A1MAPTTSHR | |
| SCHEMBL19981138 | 0.72 | BMP1 (0.49) | KDM4EALDH1A1DPP4DPP8DPP9 | |
| SCHEMBL18077951 | 0.71 | CD274 (0.53) | KDM4ELMNAALDH1A1MAPTTSHR | |
| SCHEMBL5412130 | 0.68 | BMP1 (0.56) | BMP1MMP2 | |
| SCHEMBL5404213 | 0.68 | BMP1 (0.56) | BMP1MMP2 | |
| SCHEMBL18078143 | 0.67 | VSIR (0.52) | BMP1 | |
| SCHEMBL19871033 | 0.67 | BMP1 (0.31) | BMP1 | |
| SCHEMBL19981135 | 0.66 | BMP1 (0.45) | LMNATSHRDPP4DPP7BMP1 | |
| SCHEMBL18078144 | 0.66 | VSIR (0.50) | BMP1MMP2 | |
| SCHEMBL22677564 | 0.66 | VSIR (0.43) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |