Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984805 | 0.60 | NPY5R (0.37) | POLBPKMMAPTNPY5RALDH1A1 | |
| Morinamide SCHEMBL2270538 | 0.60 | GFER (0.66) | POLBPKMMAPTNPC1RAB9A | |
| SCHEMBL29834822 | 0.59 | SMN1; SMN2 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL26922576 | 0.59 | SMN1; SMN2 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2217005 | 0.59 | SMN1; SMN2 (0.56) | POLBNPC1RAB9AHSD17B10CYP1A2 | |
| SCHEMBL17327625 | 0.58 | TDP1 (0.38) | POLBMAPTNPC1NPY5RL3MBTL1 | |
| SCHEMBL21722397 | 0.58 | NPC1 (0.50) | POLBPKMMAPTHTTNPC1 | |
| Morinamide SCHEMBL29464523 | 0.58 | GFER (0.67) | POLBPKMMAPTNPC1RAB9A | |
| Morinamide SCHEMBL563960 | 0.58 | GFER (0.67) | POLBPKMMAPTNPC1RAB9A | |
| SCHEMBL16508792 | 0.58 | CA12 (0.45) | POLBHTTNPY5RTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |