Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PIEZO1 | Q92508 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984850 | 0.73 | HDAC6 (0.40) | HDAC6POLBPKMLRRK2GSK3B | |
| SCHEMBL19984983 | 0.66 | KDM4E (0.47) | KDM4ETERTPIEZO1MEN1ALDH1A1 | |
| SCHEMBL26777790 | 0.64 | KDM4E (0.48) | KDM4ETERTNLRP3PIEZO1MEN1 | |
| SCHEMBL19984827 | 0.63 | KDM4E (0.44) | KDM4ETERTNLRP3PIEZO1MEN1 | |
| SCHEMBL19984852 | 0.62 | KDM4E (0.37) | KDM4ETERTNLRP3PIEZO1MEN1 | |
| SCHEMBL19984831 | 0.62 | LRRK2 (0.35) | HDAC6POLBPKMLRRK2VNN1 | |
| SCHEMBL1256022 | 0.62 | LMNA (0.56) | POLBKDM4ELMNAGAAMEN1 | |
| SCHEMBL19981272 | 0.60 | POLB (0.39) | NPY5RPOLBPKMVNN1GAA | |
| SCHEMBL19331947 | 0.60 | POLB (0.38) | POLBPKMLRRK2GAAALDH1A1 | |
| SCHEMBL15599488 | 0.58 | KDM4E (0.50) | KDM4ETERTPIEZO1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |