Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15504866 | 0.77 | RAB9A (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL5795375 | 0.73 | SMN1; SMN2 (0.69) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL19981160 | 0.72 | S1PR1 (0.42) | ALDH1A1TSHRMAPTUSP2HPGD | |
| SCHEMBL12617891 | 0.71 | NOTUM (0.64) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL14339592 | 0.71 | NOTUM (0.64) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL19981321 | 0.71 | KDM4E (0.52) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL12612385 | 0.70 | RAB9A (0.63) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL15013250 | 0.69 | HTT (0.56) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL655414 | 0.68 | NOTUM (0.68) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL12477652 | 0.68 | NOTUM (0.69) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |