Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112739 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL12611874 | 0.85 | MAPT (0.67) | SMN1; SMN2NPC1RAB9ATSHRMAPT | |
| SCHEMBL19080613 | 0.83 | L3MBTL1 (0.65) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 | |
| Dimethylamine SCHEMBL7947230 | 0.83 | NOTUM (0.62) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL12612385 | 0.82 | RAB9A (0.63) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL20017688 | 0.82 | MAPT (0.64) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL1545778 | 0.82 | KMT2A (0.55) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL15133520 | 0.81 | KMT2A (0.63) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL91541 | 0.80 | NOTUM (0.68) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 | |
| Dimethylamine SCHEMBL7961636 | 0.80 | HTR1A (0.64) | SMN1; SMN2NPC1RAB9ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030211-A2 | ACYCLIC SULPHONAMIDES | VERNALIS (R & D) LIMITED (GB) | 2006-03-23 | — | — | WO | disclosed |