Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981325 | 0.91 | BMP1 (0.38) | BMP1L3MBTL1POLBTDP1NPC1 | |
| SCHEMBL19981267 | 0.88 | BMP1 (0.34) | BMP1MMP12L3MBTL1NPC1PKM | |
| SCHEMBL19981134 | 0.84 | BMP1 (0.39) | BMP1MMP12L3MBTL1POLBTDP1 | |
| SCHEMBL19981337 | 0.83 | BMP1 (0.42) | BMP1MMP12L3MBTL1POLBTDP1 | |
| SCHEMBL19981329 | 0.81 | VSIR (0.44) | BMP1MMP12L3MBTL1POLBTDP1 | |
| SCHEMBL19981139 | 0.79 | POLB (0.40) | BMP1MMP12L3MBTL1POLBTDP1 | |
| SCHEMBL19981266 | 0.79 | BMP1 (0.37) | BMP1L3MBTL1POLBTDP1NPC1 | |
| SCHEMBL19981170 | 0.78 | BMP1 (0.36) | BMP1L3MBTL1POLBTDP1NPC1 | |
| SCHEMBL19981344 | 0.74 | BMP1 (0.41) | BMP1L3MBTL1POLBTDP1NPC1 | |
| SCHEMBL19867043 | 0.73 | VSIR (0.51) | BMP1L3MBTL1POLBTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |