SCHEMBL19981399

SCHEMBL19981399

CCS(=O)(=O)c1cc(C(F)(F)F)ccc1-c1ncc(-c2cnn(C(F)(F)F)c2)n1C

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 10/20 0.36
FEN1 P39748 10/20 0.36
DDR1 Q08345 6/20 0.35
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
SCN9A Q15858 1/20 0.33
PTGDR2 Q9Y5Y4 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29308350 0.90 FLT3 (0.40) ALOX5APFEN1DDR1SCN9A
SCHEMBL18751256 0.87 TP53 (0.44) ALOX5APFEN1DDR1TP53POLB
SCHEMBL19219734 0.85 TP53 (0.47) ALOX5APFEN1DDR1TP53POLB
SCHEMBL18751266 0.82 ALOX5AP (0.41) ALOX5APFEN1TP53POLBGAA
SCHEMBL30843066 0.78 DDR1 (0.39) ALOX5APFEN1DDR1SCN9A
SCHEMBL19017140 0.78 DDR1 (0.39) ALOX5APFEN1DDR1PTGDR2
SCHEMBL19017507 0.78 DDR1 (0.41) ALOX5APFEN1DDR1PTGDR2
SCHEMBL29755613 0.77 ALOX5AP (0.39) ALOX5APFEN1DDR1PTGDR2
SCHEMBL18988945 0.77 ALOX5AP (0.39) ALOX5APFEN1DDR1PTGDR2
SCHEMBL18989081 0.76 ALOX5AP (0.39) ALOX5APFEN1DDR1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2022-02-03 US disclosed
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2019-06-20 US disclosed
WO-2018052035-A1 DIARYL AZOLE COMPOUND AND PESTICIDE 日本曹達株式会社 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L ALOX5AP 4111/4885FEN1 4477/4885DDR1 1096/4885
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L ALOX5AP 4111/4885FEN1 4477/4885DDR1 1096/4885
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L ALOX5AP 4111/4885FEN1 4477/4885DDR1 1096/4885
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L ALOX5AP 4111/4885FEN1 4477/4885DDR1 1096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.