Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 10/20 | 0.40 |
| ▸ | FEN1 | P39748 | 10/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18751256 | 0.96 | TP53 (0.44) | TP53GAAMAPTPOLBDDR1 | |
| SCHEMBL18751266 | 0.89 | ALOX5AP (0.41) | TP53GAAMAPTPOLBALOX5AP | |
| SCHEMBL29308350 | 0.86 | FLT3 (0.40) | DDR1ALOX5APFEN1 | |
| SCHEMBL19981399 | 0.85 | ALOX5AP (0.36) | TP53GAAMAPTPOLBDDR1 | |
| SCHEMBL29308351 | 0.82 | TP53 (0.47) | TP53GAAMAPTPOLBDDR1 | |
| SCHEMBL30843066 | 0.82 | DDR1 (0.39) | DDR1ALOX5APFEN1 | |
| SCHEMBL19017140 | 0.82 | DDR1 (0.39) | DDR1ALOX5APFEN1PTGDR2 | |
| SCHEMBL19017507 | 0.82 | DDR1 (0.41) | DDR1ALOX5APFEN1PTGDR2 | |
| SCHEMBL18988945 | 0.81 | ALOX5AP (0.39) | DDR1ALOX5APFEN1PTGDR2 | |
| SCHEMBL29755613 | 0.81 | ALOX5AP (0.39) | DDR1ALOX5APFEN1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10021880-B2 | Diarylimidazole compound and harmful organism control agent | NIPPON SODA CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20170223958-A1 | DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10021880-B2 | Diarylimidazole compound and harmful organism control agent | NOX1, L3MBTL1, MRM1 | TP53 3609/4885GAA 3504/4885MAPT 4473/4885 |
| US-20170223958-A1 | DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NOX1, L3MBTL1, MRM1 | TP53 3609/4885GAA 3504/4885MAPT 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.