SCHEMBL19981444

SCHEMBL19981444

CCS(=O)(=O)c1ccc(-n2cnc(C)n2)nc1-c1ncc(Br)n1C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29308357 0.83 LMNA (0.33) LMNAMAPT
SCHEMBL18854930 0.79 LMNA (0.32) LMNAMAPT
SCHEMBL19981440 0.78 DDR1 (0.32) MAPT
SCHEMBL29455621 0.77 PDE2A (0.39) LMNAMAPT
SCHEMBL19981447 0.77 PDE2A (0.39) LMNAMAPT
SCHEMBL21020024 0.75 DDR1 (0.33) LMNA
SCHEMBL18866373 0.75 POLB (0.40) LMNA
SCHEMBL17383211 0.74 DDR1 (0.40)
SCHEMBL18854929 0.73 BRD4 (0.30)
SCHEMBL25847648 0.72 KDM4E (0.33) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
CN-109689630-B Diaryl azole compound and pest control agent 日本曹达株式会社 2022-06-03 CN disclosed
EP-3514146-B1 DIARYL- AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO (JP) 2022-03-16 EP disclosed
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2022-02-03 US disclosed
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2019-06-20 US disclosed
CN-109689630-A Diaryl azole compound and pest control agent 日本曹达株式会社 2019-04-26 CN disclosed
WO-2018052035-A1 DIARYL AZOLE COMPOUND AND PESTICIDE 日本曹達株式会社 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L LMNA 3711/4885MAPT 3768/4885
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L LMNA 3711/4885MAPT 3768/4885
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L LMNA 3711/4885MAPT 3768/4885
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L LMNA 3711/4885MAPT 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.