Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13303500 | 0.79 | UGT2B17 (0.35) | ADRA2AADRA2BADRA2C | |
| SCHEMBL11987727 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL11987814 | 0.75 | NPC1 (0.38) | — | |
| SCHEMBL17970193 | 0.73 | UGT2B17 (0.40) | — | |
| SCHEMBL14140631 | 0.70 | ADRA2A (0.50) | ADRA2AADRA2BADRA2C | |
| SCHEMBL19981490 | 0.69 | UGT2B17 (0.40) | — | |
| SCHEMBL13303507 | 0.69 | UGT2B17 (0.33) | — | |
| SCHEMBL11987736 | 0.69 | UGT2B17 (0.33) | — | |
| SCHEMBL11987801 | 0.69 | HPGD (0.35) | — | |
| SCHEMBL12894433 | 0.65 | CNR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |