SCHEMBL19981545

SCHEMBL19981545

CCCCC(C)N(C)CCNC

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT1 Q99873 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
EPHX1 P07099 1/20 0.38
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20922387 0.84 EPHX1 (0.38) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24378597 0.83 EPHX1 (0.48) EPHX1OPRM1
SCHEMBL22703720 0.83 EPHX1 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL18902339 0.81 DNM1 (0.35) OPRM1
SCHEMBL13363818 0.81 DNM1 (0.35) OPRM1
SCHEMBL18735410 0.81 DNM1 (0.35) OPRM1
SCHEMBL21671810 0.79 PRMT3 (0.37) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24781180 0.79 PRMT3 (0.54) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24093996 0.79 DNM1 (0.44) OPRM1
SCHEMBL12477735 0.79 PRMT3 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633542-B2 Azacyanine dyes and use thereof Ecole polytechnique fédérale de Lausanne (EPFL) (CH) 2020-04-28 US disclosed
US-20190292371-A1 AZACYANINE DYES AND USE THEREOF INTRACE MEDICAL SA (CH) 2019-09-26 US disclosed
US-20180079906-A1 AZACYANINE DYES AND USE THEREOF Ecole polytechnique fédérale de Lausanne (EPFL) (CH) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292371-A1 AZACYANINE DYES AND USE THEREOF INMT, AZI2, MYADM PRMT3 30/4885CARM1 61/4885PRMT6 87/4885
US-10633542-B2 Azacyanine dyes and use thereof INMT, AZI2, MYADM PRMT3 30/4885CARM1 61/4885PRMT6 87/4885
US-20180079906-A1 AZACYANINE DYES AND USE THEREOF INMT, AZI2, MYADM PRMT3 30/4885CARM1 61/4885PRMT6 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.