Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24688718 | 0.98 | LMNA (0.50) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL22212724 | 0.92 | ALDH1A1 (0.42) | LMNAALDH1A1TDP1DNM1TSHR | |
| SCHEMBL18978505 | 0.92 | LMNA (0.54) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL25531477 | 0.87 | ALDH1A1 (0.46) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL26386669 | 0.83 | LMNA (0.50) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL6057262 | 0.81 | ALDH1A1 (0.46) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL8679451 | 0.81 | LMNA (0.57) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL4072853 | 0.81 | LMNA (0.57) | LMNAOPRM1ALDH1A1TDP1DNM1 | |
| SCHEMBL15729910 | 0.79 | LMNA (0.46) | LMNAOPRM1DNM1TSHRFDPS | |
| SCHEMBL4309549 | 0.79 | LMNA (0.50) | LMNAOPRM1ALDH1A1TDP1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145936-B1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA INC (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-3295933-A1 | HYDROGELS BASED ON FUNCTIONALIZED POLYSACCHARIDES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2018-03-21 | — | — | EP | disclosed |