Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059519 | 0.81 | FFAR1 (0.54) | SCN4AALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL7223998 | 0.80 | NOTUM (0.49) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL19982393 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL7222243 | 0.73 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL19982476 | 0.71 | MEN1 (0.53) | L3MBTL1MEN1KMT2AHPGDLMNA | |
| SCHEMBL20801750 | 0.70 | SCN4A (0.50) | SCN4AALDH1A1L3MBTL1HPGDMAPT | |
| SCHEMBL11338980 | 0.70 | SCN4A (0.46) | SCN4AALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3104254 | 0.70 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL30289819 | 0.70 | SCN4A (0.46) | SCN4AALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL153461 | 0.70 | FFAR1 (0.68) | ALDH1A1L3MBTL1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296302-B1 | CHIRAL SPIRO PHOSPHORUS-NITROGEN-SULPHUR TRIDENTATE LIGAND, AND PREPARATION METHOD AND APPLICATION THEREOF | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2020-02-12 | — | — | EP | disclosed |
| US-10550138-B2 | Chiral spiro phosphorus-nirogen-sulphur tridentate ligand, preparation method and application thereof | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2020-02-04 | — | — | US | disclosed |
| US-20180141966-A1 | CHIRAL SPIRO PHOSPHORUS-NIROGEN-SULPHUR TRIDENTATE LIGAND, PREPARATION METHOD AND APPLICATION THEREOF | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| US-20180141966-A1 | CHIRAL SPIRO PHOSPHORUS-NIROGEN-SULPHUR TRIDENTATE LIGAND, PREPARATION METHOD AND APPLICATION THEREOF | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| EP-3296302-A1 | CHIRAL SPIRO PHOSPHORUS-NITROGEN-SULPHUR TRIDENTATE LIGAND, AND PREPARATION METHOD AND APPLICATION THEREOF | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2018-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141966-A1 | CHIRAL SPIRO PHOSPHORUS-NIROGEN-SULPHUR TRIDENTATE LIGAND, PREPARATION METHOD AND APPLICATION THEREOF | TST, SPR, ROR1 | SCN4A 80/4885ALDH1A1 374/4885L3MBTL1 4775/4885 |
| US-10550138-B2 | Chiral spiro phosphorus-nirogen-sulphur tridentate ligand, preparation method and application thereof | TST, SPR, ROR1 | SCN4A 80/4885ALDH1A1 374/4885L3MBTL1 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.