Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.40 |
| ▸ | GNRHR | P30968 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982612 | 0.93 | CYP1A2 (0.43) | SLC2A1KCNH2DGAT1NPBWR1FGFR1 | |
| SCHEMBL19982578 | 0.85 | SLC2A1 (0.45) | SLC2A1KCNH2DGAT1NPBWR1GNRHR | |
| SCHEMBL19982654 | 0.85 | DRD4 (0.43) | SLC2A1KCNH2DGAT1NPBWR1 | |
| SCHEMBL19970823 | 0.84 | SLC2A1 (0.49) | SLC2A1HDAC6 | |
| SCHEMBL19982561 | 0.82 | SLC2A1 (0.46) | SLC2A1KCNH2DGAT1NPBWR1GNRHR | |
| SCHEMBL19982610 | 0.79 | SLC2A1 (0.42) | SLC2A1KCNH2NPBWR1FGFR1FLT1 | |
| SCHEMBL19970822 | 0.78 | LMNA (0.45) | SLC2A1GNRHRTACR2HRH2OPRM1 | |
| SCHEMBL19970810 | 0.78 | CHEK2 (0.41) | SLC2A1KCNH2DGAT1FGFR1FLT1 | |
| SCHEMBL23843052 | 0.77 | ACACB (0.47) | SLC2A1HDAC6PTGDR2 | |
| SCHEMBL19982585 | 0.77 | DRD4 (0.42) | SLC2A1KCNH2NPBWR1FGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050771-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-22 | — | — | WO | disclosed |
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |