Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | ATIC | P31939 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.35 |
| ▸ | SENP3 | Q9H4L4 | 5/20 | 0.35 |
| ▸ | SUMO2 | P61956 | 5/20 | 0.35 |
| ▸ | SUMO1 | P63165 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17000438 | 0.82 | TTR (0.55) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL7548396 | 0.81 | TTR (0.55) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL31621937 | 0.81 | ALDH1A1 (0.57) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL1809362 | 0.81 | ALDH1A1 (0.57) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL7736713 | 0.81 | TTR (0.53) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL9178671 | 0.80 | ALDH1A1 (0.42) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL9179068 | 0.80 | CTDSP1 (0.42) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL9314959 | 0.78 | TTR (0.54) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL25990463 | 0.77 | TDP1 (0.39) | HSD17B10ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29516385 | 0.76 | TTR (0.78) | TTRAURKAAURKBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296363-A1 | AZO DYES | Kemira Oyj (FI) | 2018-03-21 | — | — | EP | disclosed |
| EP-3296362-A1 | AZO DYES | Kemira Oyj (FI) | 2018-03-21 | — | — | EP | disclosed |