Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 3/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17000438 | 0.84 | TTR (0.55) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL7736713 | 0.82 | TTR (0.53) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL1809362 | 0.82 | ALDH1A1 (0.57) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL11524521 | 0.82 | AURKA (0.54) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL31621937 | 0.82 | ALDH1A1 (0.57) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL28065855 | 0.81 | TTR (0.61) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL19982597 | 0.81 | TTR (0.51) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL6051371 | 0.80 | ALDH1A1 (0.59) | TTRHSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL27999197 | 0.80 | ALDH1A1 (0.46) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL4650278 | 0.80 | TTR (0.55) | TTRAURKAAURKBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444091-B1 | MIXING PULPS WITH POLYAMIDES OR IN COMBINATION WITH COAGULANTS, FLOCCULANTS AND/OR PARTICLES; EFFICIENCY | NALCO CHEMICAL COMPANY | 2002-09-03 | — | — | US | disclosed |
| WO-2002052102-A2 | STRUCTURALLY RIGID NONIONIC AND ANIONIC POLYMERS AS RETENTION AND DRAINAGE AIDS IN PAPERMAKING | ONDEO NALCO COMPANY (US) | 2002-07-04 | — | — | WO | disclosed |