Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPEPLD | Q6IQ20 | 15/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975088 | 0.89 | CTSD (0.39) | NAPEPLDALDH1A1BRD4HTTCTSD | |
| SCHEMBL19974949 | 0.80 | NAPEPLD (0.38) | NAPEPLDALDH1A1BRD4HTTCTSD | |
| SCHEMBL19975145 | 0.71 | NPC1 (0.30) | CTSDKDM4E | |
| SCHEMBL19974688 | 0.70 | CTSL (0.41) | NAPEPLDBRD4CTSDCTSLCTSS | |
| SCHEMBL21183511 | 0.69 | NAPEPLD (0.39) | NAPEPLDBRD4CTSD | |
| SCHEMBL19975034 | 0.67 | KDM4E (0.34) | CTSDKDM4E | |
| SCHEMBL19974924 | 0.67 | NAPEPLD (0.40) | NAPEPLDALDH1A1BRD4CTSDKDM4E | |
| SCHEMBL19974959 | 0.66 | CTSD (0.30) | CTSD | |
| SCHEMBL19975158 | 0.66 | KDM4E (0.32) | CTSDKDM4E | |
| SCHEMBL21183525 | 0.64 | TDP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |