Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CRAT | P43155 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539294 | 0.79 | CA12 (0.38) | PLA2G2CCA12CA1CA2MMP1 | |
| SCHEMBL8367402 | 0.79 | TAS1R3 (0.46) | PLA2G2CCA12CA1CA2MMP1 | |
| SCHEMBL422585 | 0.78 | — | — | |
| SCHEMBL14007401 | 0.77 | PLA2G2C (0.40) | PLA2G2CCA12CA1CA2MMP1 | |
| SCHEMBL17919112 | 0.75 | ALDH1A1 (0.41) | PLA2G2CCA12CA1CA2MMP1 | |
| SCHEMBL7041741 | 0.75 | PLA2G2C (0.39) | PLA2G2CCA12CA1CA2MMP1 | |
| SCHEMBL13715798 | 0.75 | PLA2G2C (0.59) | PLA2G2CCA1CA2PLA2G2A | |
| SCHEMBL8261926 | 0.73 | PLA2G2C (0.38) | PLA2G2CCA12CA1CA2MMP1 | |
| SCHEMBL8513712 | 0.73 | PLA2G2C (0.57) | PLA2G2CCA1PLA2G2A | |
| SCHEMBL15959880 | 0.73 | GRN (0.34) | CA1CA2GRNSORT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |