Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | CTSH | P09668 | 3/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982898 | 0.84 | EPHX1 (0.35) | EPHX1CTSKCTSLCTSBCTSH | |
| SCHEMBL19974754 | 0.81 | EPHX1 (0.39) | HPGDKMT2AEPHX1METAP2SMN1; SMN2 | |
| SCHEMBL19975141 | 0.70 | EPHX1 (0.41) | HPGDKMT2AEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL19974838 | 0.65 | SMN1; SMN2 (0.40) | KMT2AEPHX1METAP2TSHRSMN1; SMN2 | |
| SCHEMBL19975400 | 0.65 | SMN1; SMN2 (0.40) | KMT2AEPHX1METAP2TSHRSMN1; SMN2 | |
| SCHEMBL26980521 | 0.65 | EPHX1 (0.58) | HPGDKMT2AEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL14602767 | 0.65 | EPHX1 (0.58) | HPGDKMT2AEPHX1SMN1; SMN2NPC1 | |
| SCHEMBL13209041 | 0.65 | EPHX1 (0.58) | HPGDKMT2AEPHX1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL14973792 | 0.64 | METAP2 (0.56) | HPGDKMT2AEPHX1METAP2CPB2 | |
| SCHEMBL19974956 | 0.63 | ADH1C (0.50) | HPGDEPHX1TSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |