Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983751 | 0.89 | GPR84 (0.40) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983944 | 0.83 | GPR84 (0.40) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983858 | 0.83 | GPR84 (0.40) | GPR84CHRNB2CHRNA7CHRNA4HTR2A | |
| SCHEMBL19983849 | 0.82 | GPR84 (0.40) | GPR84CHRNB2CHRNA7CHRNA4HTR2A | |
| SCHEMBL19983891 | 0.82 | GPR84 (0.49) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984124 | 0.81 | GPR84 (0.42) | GPR84CHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL19983863 | 0.81 | GPR84 (0.38) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984153 | 0.80 | GPR84 (0.40) | GPR84CHRNB2CHRNA7CHRNA4HTR2A | |
| SCHEMBL19983754 | 0.80 | HTR2A (0.45) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984001 | 0.80 | MAPK8 (0.48) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |