Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983892 | 0.87 | PTGS2 (0.46) | GPR84TDO2PTGS2CHRNB2CHRNA7 | |
| SCHEMBL19984195 | 0.84 | LRRK2 (0.41) | PTGS2CHRNB2CHRNA7CHRNA4CYP3A4 | |
| SCHEMBL19984015 | 0.84 | GRM4 (0.39) | GPR84TDO2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983913 | 0.82 | GPR84 (0.38) | GPR84TDO2PTGS2CHRNB2CHRNA7 | |
| SCHEMBL19983828 | 0.81 | LMNA (0.38) | GPR84CHRNB2CHRNA7CHRNA4GRM4 | |
| SCHEMBL19983738 | 0.81 | GPR84 (0.39) | GPR84PTGS2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984124 | 0.80 | GPR84 (0.42) | GPR84CHRNB2CHRNA7CHRNA4HTR1A | |
| SCHEMBL19983890 | 0.80 | EGFR (0.43) | GPR84CHRNB2CHRNA7CHRNA4GRM4 | |
| SCHEMBL19984142 | 0.80 | BACE1 (0.39) | GPR84GRM4 | |
| SCHEMBL19983904 | 0.80 | GRM4 (0.45) | GRM4ALDH1A1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |