Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.49 |
| ▸ | MPO | P05164 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984003 | 0.89 | GPR84 (0.50) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19984005 | 0.88 | HTR2A (0.44) | GPR84HTR2AALKBH5FTONR3C1 | |
| SCHEMBL19984030 | 0.87 | GPR84 (0.48) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19983748 | 0.87 | GPR84 (0.50) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19983944 | 0.87 | GPR84 (0.40) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19983847 | 0.86 | TBXAS1 (0.42) | GPR84HTR2AHTR1ANR3C1CHRNB2 | |
| SCHEMBL19983867 | 0.86 | HTR2C (0.42) | HTR2AHTR1AHTR6HTR2CCHRNB2 | |
| SCHEMBL19984197 | 0.86 | GPR84 (0.49) | GPR84HTR2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983751 | 0.86 | GPR84 (0.40) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19983983 | 0.85 | GPR84 (0.44) | GPR84MPOHTR2AHTR1AALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |