Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984215 | 0.88 | GAA (0.47) | HTR2AMEN1KMT2AHTR6GPR84 | |
| SCHEMBL19984242 | 0.86 | HTR2A (0.44) | HTR2AMEN1KMT2AHTR6GPR84 | |
| SCHEMBL19984003 | 0.86 | GPR84 (0.50) | HTR2AHTR6GPR84MAPK14HTR1A | |
| SCHEMBL19983754 | 0.85 | HTR2A (0.45) | HTR2AGPR84HTR1DKDM4EALDH1A1 | |
| SCHEMBL19983831 | 0.85 | HTR2A (0.49) | HTR2AMEN1KMT2AHTR6GPR84 | |
| SCHEMBL19984134 | 0.84 | HTR2A (0.41) | HTR2AMEN1KMT2AHTR6GPR84 | |
| SCHEMBL19983772 | 0.84 | GPR84 (0.48) | HTR2AGPR84CYP1A2TRPM8 | |
| SCHEMBL19984124 | 0.83 | GPR84 (0.42) | HTR2AMEN1KMT2AGPR84HTR1A | |
| SCHEMBL19983711 | 0.82 | CDK2 (0.40) | HTR2AGPR84CDK2 | |
| SCHEMBL19983741 | 0.82 | AKR1C3 (0.51) | HTR2AMEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |