Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984215 | 0.83 | GAA (0.47) | MAPTALDH1A1GAASMN1; SMN2HTR2A | |
| SCHEMBL19983830 | 0.82 | HTR2A (0.48) | MAPTALDH1A1SMN1; SMN2HTR2AMTNR1A | |
| SCHEMBL19983831 | 0.80 | HTR2A (0.49) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL19984134 | 0.78 | HTR2A (0.41) | MAPTMAPK1LMNASMN1; SMN2HTR2A | |
| SCHEMBL19984156 | 0.74 | MEN1 (0.38) | MAPTTDP1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL19984222 | 0.74 | CDK2 (0.41) | MAPK1LMNASMN1; SMN2HTR2AMTNR1A | |
| SCHEMBL19984013 | 0.74 | HTR2A (0.35) | ALDH1A1SMN1; SMN2HTR2AMTNR1AMTNR1B | |
| SCHEMBL19984242 | 0.73 | HTR2A (0.44) | MAPTALDH1A1SMN1; SMN2HTR2AMTNR1A | |
| SCHEMBL19983869 | 0.73 | MMP2 (0.46) | AKR1C3ALDH1A1LMNASMN1; SMN2HTR2A | |
| SCHEMBL19983880 | 0.73 | MEN1 (0.36) | ALDH1A1SMN1; SMN2HTR2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |