Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19199913 | 0.73 | EPHX1 (0.44) | EPHX1TDP1MAN2B1GAAMEN1 | |
| SCHEMBL30233805 | 0.71 | TDP1 (0.47) | EPHX1TDP1MAN2B1GAAMEN1 | |
| SCHEMBL26730931 | 0.70 | GAA (0.45) | EPHX1TDP1MAN2B1GAAMEN1 | |
| SCHEMBL12648114 | 0.70 | EPHX1 (0.55) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL23857736 | 0.69 | TDP1 (0.43) | EPHX1TDP1MAN2B1GAAMEN1 | |
| SCHEMBL590365 | 0.69 | TDP1 (0.49) | EPHX1TDP1MAN2B1GAAMEN1 | |
| SCHEMBL15127550 | 0.69 | KMT2A (0.49) | EPHX1TDP1MAN2B1GAAMEN1 | |
| SCHEMBL14932472 | 0.69 | TDP1 (0.42) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL30227747 | 0.68 | MEN1 (0.38) | L3MBTL1EPHX1TDP1MAN2B1GAA | |
| SCHEMBL23028395 | 0.67 | TDP1 (0.50) | EPHX1TDP1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079860-A1 | STIMULUS-RESPONSIVE POLY(LACTIC-CO-GLYCOLIC)-BASED POLYMERS AND NANOPARTICLES FORMED THEREFROM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079860-A1 | STIMULUS-RESPONSIVE POLY(LACTIC-CO-GLYCOLIC)-BASED POLYMERS AND NANOPARTICLES FORMED THEREFROM | LGMN, CASP12, LITAF | L3MBTL1 2693/4885EPHX1 3470/4885TDP1 2967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.