Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.60 |
| ▸ | CSNK1A1 | P48729 | 6/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.59 |
| ▸ | GSK3B | P49841 | 5/20 | 0.59 |
| ▸ | CSNK1G2 | P78368 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.51 |
| ▸ | DDX3X | O00571 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986068 | 0.81 | CSNK1D (0.85) | AKR1C3CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL30020996 | 0.80 | MEN1 (0.75) | AKR1C3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL239690 | 0.80 | MEN1 (0.75) | AKR1C3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18236256 | 0.79 | AKR1C3 (0.63) | AKR1C3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1999901 | 0.79 | AKR1C3 (0.63) | AKR1C3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18415225 | 0.76 | AKR1C3 (0.59) | AKR1C3CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL1998475 | 0.76 | AKR1C3 (0.59) | AKR1C3MEN1KMT2AABCG2DDX3X | |
| SCHEMBL28050241 | 0.76 | RAB9A (0.68) | AKR1C3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3766427 | 0.75 | AKR1C3 (1.00) | AKR1C3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13500676 | 0.75 | ALDH1A1 (0.69) | IRAK4NPC1RAB9AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076106-A1 | 2-(Phenylamino) Benzimidazole Derivatives and Their Use as Modulators of Small- Conductance Calcuim-Activated Potassium Channels | NEUROSEARCH A/S (DK) | 2009-03-19 | — | — | US | claimed |
| US-7960561-B2 | 2-(phenylamino) benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels | NEUROSEARCH A/S (DK) | 2011-06-14 | — | — | US | disclosed |
| US-20090076106-A1 | 2-(Phenylamino) Benzimidazole Derivatives and Their Use as Modulators of Small- Conductance Calcuim-Activated Potassium Channels | NEUROSEARCH A/S (DK) | 2009-03-19 | — | — | US | disclosed |
| EP-1896427-A2 | NOVEL 2-(PHENYLAMINO)BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NeuroSearch A/S (DK) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006136580-A2 | 2-(PHENYLAMINO)BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076106-A1 | 2-(Phenylamino) Benzimidazole Derivatives and Their Use as Modulators of Small- Conductance Calcuim-Activated Potassium Channels | KCNN2, KCNN1, KCNN3 | AKR1C3 3134/4885IRAK4 2074/4885CSNK1A1 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.