Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.31 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19975396 | 0.89 | LOXL2 (0.31) | LOXL2 | |
| Hydrochloric Acid SCHEMBL21273306 | 0.89 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL19975384 | 0.75 | MLYCD (0.38) | — | |
| SCHEMBL29225034 | 0.75 | ESR2 (0.34) | ESR2 | |
| SCHEMBL12341805 | 0.75 | SMN1; SMN2 (0.37) | ESR2 | |
| SCHEMBL19984742 | 0.74 | PDE10A (0.32) | — | |
| SCHEMBL628287 | 0.73 | GSK3B (0.37) | ESR2SLC8A1 | |
| SCHEMBL19975191 | 0.71 | L3MBTL1 (0.33) | — | |
| SCHEMBL19975363 | 0.71 | IDO1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL19975373 | 0.70 | LOXL2 (0.31) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |