Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.37 |
| ▸ | KDM6B | O15054 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 3/20 | 0.33 |
| ▸ | CDK8 | P49336 | 3/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984499 | 0.87 | KDM4E (0.39) | TDP1L3MBTL1KDM4EALDH1A1THRB | |
| SCHEMBL17085855 | 0.82 | L3MBTL1 (0.48) | TDP1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL19984562 | 0.81 | MAPT (0.34) | MAPTL3MBTL1ALDH1A1GAAIDO1 | |
| SCHEMBL19984503 | 0.78 | KDM4C (0.37) | KDM4CKDM6BTDP1MEN1KMT2A | |
| SCHEMBL17086268 | 0.73 | TP53 (0.51) | TDP1MAPTL3MBTL1ALDH1A1THRB | |
| SCHEMBL19984493 | 0.72 | HPGD (0.49) | TDP1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL17085917 | 0.71 | KMT2A (0.50) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL17086097 | 0.69 | KCNK3 (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL18666975 | 0.69 | TP53 (0.49) | TDP1MAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL17086219 | 0.68 | TP53 (0.39) | TDP1MEN1KMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |