Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CCNC | P24863 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984564 | 0.87 | KDM4C (0.37) | KDM4EALDH1A1GAACCNCCDK8 | |
| SCHEMBL18666975 | 0.83 | TP53 (0.49) | KDM4EALDH1A1GAAL3MBTL1TP53 | |
| SCHEMBL19984498 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1GLAGAACCNC | |
| SCHEMBL19984562 | 0.78 | MAPT (0.34) | ALDH1A1GAAL3MBTL1TP53BLM | |
| SCHEMBL17085917 | 0.70 | KMT2A (0.50) | KDM4EALDH1A1GAAHPGDHTT | |
| SCHEMBL17085855 | 0.69 | L3MBTL1 (0.48) | KDM4EALDH1A1GAAL3MBTL1TP53 | |
| SCHEMBL2921667 | 0.69 | CES1 (0.53) | KDM4EGLAGAACYP46A1L3MBTL1 | |
| SCHEMBL17086097 | 0.69 | KCNK3 (0.43) | TP53HTT | |
| SCHEMBL17086219 | 0.68 | TP53 (0.39) | L3MBTL1TP53POLBTHRBBLM | |
| SCHEMBL19984503 | 0.66 | KDM4C (0.37) | KDM4EALDH1A1CCNCCDK8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |