Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984564 | 0.81 | KDM4C (0.37) | MAPTL3MBTL1GAAIDO1ALDH1A1 | |
| SCHEMBL18666978 | 0.81 | L3MBTL1 (0.51) | MAPTTP53TSHRMAPK1BLM | |
| SCHEMBL19984515 | 0.75 | TP53 (0.33) | MAPTTP53CYP3A4TSHRMAPK1 | |
| SCHEMBL27892040 | 0.66 | ALDH1A1 (0.33) | MAPTCYP3A4GAAALDH1A1 | |
| SCHEMBL23018616 | 0.66 | L3MBTL1 (0.54) | MAPTTP53TSHRMAPK1BLM | |
| SCHEMBL19984493 | 0.65 | HPGD (0.49) | MAPTTP53BLMSMN1; SMN2L3MBTL1 | |
| SCHEMBL17086268 | 0.64 | TP53 (0.51) | MAPTTP53BLMSMN1; SMN2L3MBTL1 | |
| SCHEMBL1092103 | 0.64 | CES1 (0.62) | CASP7L3MBTL1TGM2ALDH1A1ALDH2 | |
| SCHEMBL7220609 | 0.63 | GAA (0.41) | MAPTL3MBTL1GAAIDO1 | |
| SCHEMBL23018474 | 0.62 | L3MBTL1 (0.49) | MAPTTP53CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |