Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31274029 | 0.82 | GSK3B (0.55) | GSK3BALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL19984701 | 0.80 | GSK3B (0.55) | GSK3BKMT2AMAPTRAB9ANPC1 | |
| SCHEMBL19984702 | 0.79 | HDAC3 (0.58) | GSK3BALDH1A1MAPTLMNARAB9A | |
| SCHEMBL6902376 | 0.79 | GSK3B (0.48) | GSK3BALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL6902380 | 0.79 | GSK3B (0.48) | GSK3BALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL507140 | 0.79 | GSK3B (0.57) | GSK3BALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL21470081 | 0.79 | GSK3B (0.57) | GSK3BALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL10782076 | 0.78 | ALDH1A1 (0.58) | GSK3BALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL19984837 | 0.78 | MEN1 (0.51) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL19642670 | 0.78 | ALDH1A1 (0.62) | GSK3BALDH1A1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306986-B1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC (US) | 2018-03-21 | — | — | EP | disclosed |