Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.48 |
| ▸ | WNT3A | P56704 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554899 | 0.86 | PARP1 (0.53) | MEN1MAPTKMT2ANPSR1TDP2 | |
| SCHEMBL8812764 | 0.84 | CTNNB1 (0.53) | MEN1MAPTKMT2ANPSR1TDP2 | |
| SCHEMBL12960171 | 0.82 | PARP1 (0.53) | MEN1MAPTKMT2ANPSR1TDP2 | |
| SCHEMBL19984703 | 0.79 | ERCC5 (0.54) | MEN1KMT2APARP1HPGDKCNH2 | |
| SCHEMBL19984840 | 0.79 | CES2 (0.57) | KMT2APARP1CTNNB1WNT3ATDP1 | |
| SCHEMBL19984698 | 0.78 | GSK3B (0.53) | MEN1MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL11341501 | 0.78 | PARP1 (0.57) | MEN1MAPTKMT2ANPSR1PARP1 | |
| SCHEMBL28728190 | 0.77 | MEN1 (0.64) | MEN1MAPTKMT2ANPSR1PARP1 | |
| SCHEMBL29456641 | 0.77 | MEN1 (0.64) | MEN1MAPTKMT2ANPSR1PARP1 | |
| SCHEMBL29062364 | 0.77 | CTNNB1 (0.70) | MEN1MAPTKMT2ANPSR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306986-B1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC (US) | 2018-03-21 | — | — | EP | disclosed |