Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984816 | 0.87 | ADAMTS4 (0.41) | PDE1APDE1BPDE1CKMT2ASMN1; SMN2 | |
| SCHEMBL19984783 | 0.86 | CTSA (0.42) | PDE1APDE1BPDE1CKMT2ASMN1; SMN2 | |
| SCHEMBL19984794 | 0.86 | KMT2A (0.41) | PDE1APDE1BPDE1CKMT2ASMN1; SMN2 | |
| SCHEMBL19984784 | 0.78 | PTK2 (0.47) | PDE1APDE1BPDE1CKMT2ASMN1; SMN2 | |
| SCHEMBL19984981 | 0.63 | CYP1A2 (0.40) | SMN1; SMN2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL19984806 | 0.62 | KMT2A (0.41) | KMT2ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL19984813 | 0.62 | KMT2A (0.42) | KMT2ASMN1; SMN2ALDH1A1HPGDGLA | |
| SCHEMBL19984798 | 0.62 | CTSA (0.47) | KMT2ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL19984807 | 0.61 | TP53 (0.43) | KMT2ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL19984799 | 0.61 | KMT2A (0.43) | KMT2ASMN1; SMN2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |