Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDE1A | P54750 | 2/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984783 | 0.91 | CTSA (0.42) | KMT2APDE1APDE1BPDE1CCTSS | |
| SCHEMBL19984794 | 0.87 | KMT2A (0.41) | KMT2APDE1APDE1BPDE1CCTSS | |
| SCHEMBL19984800 | 0.87 | PDE1A (0.41) | KMT2APDE1APDE1BPDE1CALDH1A1 | |
| SCHEMBL19984799 | 0.76 | KMT2A (0.43) | ADAMTS4ADAMTS5KMT2ACTSSCTSK | |
| SCHEMBL19984825 | 0.75 | ADAMTS4 (0.57) | ADAMTS4ADAMTS5KMT2ACTSSCTSK | |
| SCHEMBL18078747 | 0.74 | ADAMTS4 (0.45) | ADAMTS4ADAMTS5KMT2ACTSSCTSK | |
| SCHEMBL19866363 | 0.74 | ADAMTS4 (0.45) | ADAMTS4ADAMTS5KMT2ACTSSCTSK | |
| SCHEMBL19984784 | 0.74 | PTK2 (0.47) | KMT2APDE1APDE1BPDE1CALDH1A1 | |
| SCHEMBL19984823 | 0.73 | ADAMTS4 (0.55) | ADAMTS4ADAMTS5KMT2ACTSSCTSK | |
| SCHEMBL19984851 | 0.72 | CTSS (0.43) | ADAMTS4ADAMTS5KMT2ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |