Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984794 | 0.77 | KMT2A (0.41) | KMT2AGLAIKBKBALDH1A1NPC1 | |
| SCHEMBL19984996 | 0.74 | ANO1 (0.45) | KMT2AGLAALDH1A1NPC1RAB9A | |
| SCHEMBL19984971 | 0.73 | ADAMTS4 (0.45) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19984787 | 0.73 | VDR (0.46) | KMT2AALDH1A1SMN1; SMN2THRBHPGD | |
| SCHEMBL19984807 | 0.73 | TP53 (0.43) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19984856 | 0.72 | CTSS (0.44) | KMT2AGLAIKBKBALDH1A1NPC1 | |
| SCHEMBL19984813 | 0.72 | KMT2A (0.42) | KMT2AGLAIKBKBALDH1A1NPC1 | |
| SCHEMBL19984853 | 0.72 | CTSS (0.44) | KMT2AGLAIKBKBALDH1A1NPC1 | |
| SCHEMBL18078745 | 0.71 | VSIR (0.48) | KMT2AGLAIKBKBALDH1A1NPC1 | |
| SCHEMBL19866358 | 0.71 | VSIR (0.48) | KMT2AGLAIKBKBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |