Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984777 | 0.92 | CA12 (0.48) | ACP3PBRM1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL5941221 | 0.84 | PBRM1 (0.62) | ACP3PBRM1CA4CNR2ALDH1A1 | |
| SCHEMBL8429413 | 0.84 | PBRM1 (0.62) | ACP3PBRM1CA4CNR2ALDH1A1 | |
| SCHEMBL19984901 | 0.84 | CNR2 (0.50) | CNR2ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL15617631 | 0.83 | ACP3 (0.56) | ACP3PBRM1CA4CNR2ALDH1A1 | |
| SCHEMBL19984820 | 0.82 | LMNA (0.44) | ALDH1A1L3MBTL1LMNACYP2D6TSHR | |
| SCHEMBL477466 | 0.80 | ACP3 (0.61) | ACP3PBRM1CA4CNR2ALDH1A1 | |
| SCHEMBL6873530 | 0.80 | ACP3 (0.61) | ACP3PBRM1CA4CNR2ALDH1A1 | |
| SCHEMBL477621 | 0.80 | ACP3 (0.61) | ACP3PBRM1CA4CNR2ALDH1A1 | |
| SCHEMBL477389 | 0.80 | ACP3 (0.61) | ACP3PBRM1CA4CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306986-B1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC (US) | 2018-03-21 | — | — | EP | disclosed |