Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984777 | 0.91 | CA12 (0.48) | TDP1ALDH1A1L3MBTL1TSHRMAPK1 | |
| SCHEMBL19984778 | 0.84 | TSHR (0.54) | CNR2HPGDCYP19A1TDP1L3MBTL1 | |
| SCHEMBL19984905 | 0.84 | GAA (0.51) | CNR2GAAHPGDCYP19A1TDP1 | |
| SCHEMBL19984817 | 0.84 | ACP3 (0.54) | CNR2ALDH1A1L3MBTL1TSHRMEN1 | |
| SCHEMBL1349310 | 0.81 | GAA (0.55) | CNR2GAAHPGDCYP19A1TDP1 | |
| SCHEMBL3693512 | 0.78 | BRD4 (0.54) | CNR2GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL19984686 | 0.77 | IDO1 (0.47) | CNR2HPGDTDP1L3MBTL1TSHR | |
| SCHEMBL15342382 | 0.77 | SLC2A1 (0.59) | CNR2GAAHPGDCYP19A1TDP1 | |
| SCHEMBL2226770 | 0.76 | — | — | |
| SCHEMBL154527 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306986-B1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC (US) | 2018-03-21 | — | — | EP | disclosed |