Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.59 |
| ▸ | WNT3A | P56704 | 2/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269548 | 0.86 | HSD11B1 (0.64) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL4637827 | 0.86 | CES2 (0.62) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL1305114 | 0.86 | CES2 (0.67) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL29588852 | 0.86 | CES2 (0.67) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL30416831 | 0.85 | ALDH1A1 (0.69) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL31557732 | 0.85 | CES2 (0.61) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL27363307 | 0.85 | CES2 (0.61) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL11193938 | 0.85 | CES2 (0.61) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL4722288 | 0.85 | ALDH1A1 (0.69) | CES2CES1CTNNB1WNT3APARP1 | |
| SCHEMBL31557720 | 0.85 | CES2 (0.61) | CES2CES1CTNNB1WNT3APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385782-A | Mechanochemical synthesis method of benzoyl compound | 兰州大学 | 2022-11-25 | — | — | CN | disclosed |
| EP-2306986-B1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC (US) | 2018-03-21 | — | — | EP | disclosed |